PLMA 100 Photopolymerizable Hydrogel
PLMA PHOTOPOLYMERIZABLE HYDROGEL is a xeno-free, animal serum-free, bioactive platelet lysates-based platform that provides physiologically relevant microenvironments for cells cultured in vitro. The precursor solution is easily prepared by reconstituting PLMA lyophilizate in an aqueous solution with a photoinitiator. Afterwards it can be cured upon light exposure to form a hydrogel with tuneable mechanical properties. PLMA Photopolymerizable Hydrogels provide great control over gelation time and matrix stiffness, enabling researchers to create the cell culture environment that better fits their needs.
PLMA 100 PHOTOPOLYMERIZABLE HYDROGEL is composed of several proteins, including growth
factors and cytokines. These bioactive proteins are known to be key components involved in cell adhesion
and proliferation processes.
PLMA 100 PHOTOPOLYMERIZABLE HYDROGEL has
tunable mechanical properties adjusted by the concentration
of PLMA 100 lyophilizate in the precursor solution. It is
therefore possible to obtain hydrogels with different
stiffnesses this way closely mimicking the mechanical
properties of native tissues.
PLMA 100 PHOTOPOLYMERIZABLE HYDROGEL applied as a 3D platform for cell culture supports the
culture of different cells, including human-derived stem cells (hSCs) and cancer cells (MG-63, SaOS-2 and
A549) up to 14 days. Due to their richness in growth factors and other bioactive proteins it is also possible to
use such platforms to culture cells in xeno-free conditions, this way avoiding the use of animal-derived serum supplements.